Dr. Althea 345 Relief Cream
Quick verdict
- Best for:Sensitive, dehydrated, post-blemish skin that wants a light daily moisturizer
- Skip if:You need a rich night cream or expect a moisturizer to clear acne on its own
- Key ingredient:Rice-derived PDRN + niacinamide
A lightweight vegan gel cream formulated with rice-derived PDRN, niacinamide, ceramide, hyaluronic acid, and soothing plant ingredients to hydrate sensitive, blemish-prone skin without a heavy finish.
Our verdict
What stands out
- Lightweight Gel-Cream Texture — Delivers moisture with a silky finish that does not feel excessively rich
- Rice-Derived PDRN — Contains sodium DNA derived from rice bran rather than salmon-derived PDRN
- Niacinamide — Helps improve the appearance of dullness and uneven-looking skin tone
- Ceramide NP — Supports moisture retention and a healthier-looking skin barrier
- Soothing Ingredient Blend — Centella, tea tree leaf water, madecassoside, and panthenol help support sensitive-feeling skin
- Non-Comedogenic Tested — Formulated and tested with acne-prone skin in mind, according to the brand
Key ingredients
- Niacinamide
- Sodium DNA from rice-bran PDRN
- Ceramide NP
- Sodium Hyaluronate
- Hydrolyzed Hyaluronic Acid
- Panthenol
- Centella Asiatica Leaf Water
- Madecassoside
- Tea Tree Leaf Water
- Beta-Glucan
- Resveratrol
How to use
Pros & Cons
Pros
- Lightweight gel-cream texture that finishes without a greasy film
- Niacinamide and ceramide NP support the moisture barrier and dull-looking tone
- Soothing blend of centella, madecassoside, panthenol and tea tree leaf water
- Vegan formula, non-comedogenic tested by the brand
- Layers comfortably under sunscreen and makeup
Cons
- Skin compatibility is mixed — some Amazon reviewers report breakouts
- Not rich enough on its own for very dry skin in winter
- Improvements in redness are supportive, not guaranteed
Frequently asked questions
Is the Dr. Althea 345 Relief Cream good for acne-prone skin?
It is non-comedogenic tested and formulated with blemish-prone skin in mind, including tea tree leaf water and centella. However, some Amazon reviewers with acne-prone skin report breakouts, so patch-test and introduce it gradually. It is a supportive moisturizer, not an acne treatment.
Can I use it with retinol or exfoliating acids?
Yes — the formula contains no conflicting actives, and its ceramide and panthenol content makes it a comfortable buffering moisturizer over retinoids or acids. Introduce only one new product at a time so you can identify the cause if irritation appears.
Is it suitable for sensitive skin?
The Ver. 2 formula is marketed for sensitive skin and includes several soothing ingredients. Individual tolerance still varies, and a small number of reviewers report irritation, so patch-testing before full-face use is the safest approach.
Does it help with redness and dark spots?
Niacinamide and madecassoside can improve the appearance of redness and uneven tone with consistent use. It is not a treatment for rosacea or melasma, and results on post-blemish marks are gradual and vary by person.
How long does one tube last?
That depends on how much you use per application. The gel-cream spreads easily, so a small amount covers the face, and most daily users find a single tube lasts several weeks to a couple of months with twice-daily use.
Who should buy it
- You want a light, layerable daily moisturizer for sensitive or dehydrated skin
- Your skin is recovering from blemishes and looks dull or uneven
- You use actives like retinoids or acids and need a gentle buffering cream
Who should skip it
- You have very dry skin that needs a rich occlusive cream
- You expect a moisturizer to clear active breakouts on its own
- Your skin has reacted to niacinamide or botanical extracts before
Disclosure: This page contains affiliate links. We may earn a commission from qualifying purchases at no additional cost to you.
Buy on AmazonWe link to Amazon and may earn a commission — at no extra cost to you.
The official ingredient list confirms that Ver. 2 contains sodium DNA, ceramide NP, multiple hydrating ingredients, and several soothing botanical components. Price and rating information may change. Check Amazon for the latest details.
Ready to try Dr. Althea 345 Relief Cream?
Check the current price and availability on Amazon.
